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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CKB
All Species:
43.33
Human Site:
Y100
Identified Species:
68.1
UniProt:
P12277
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.21
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P12277
NP_001814.2
381
42644
Y100
I
E
D
R
H
G
G
Y
K
P
S
D
E
H
K
Chimpanzee
Pan troglodytes
XP_510185
464
51502
Y183
I
E
D
R
H
G
G
Y
K
P
S
D
E
H
K
Rhesus Macaque
Macaca mulatta
XP_001112108
381
42634
Y100
I
E
D
R
H
G
G
Y
K
P
S
D
E
H
K
Dog
Lupus familis
XP_537561
394
44036
Y113
I
E
D
R
H
G
G
Y
K
P
S
D
E
H
K
Cat
Felis silvestris
Mouse
Mus musculus
Q04447
381
42695
Y100
I
E
E
R
H
G
G
Y
Q
P
S
D
E
H
K
Rat
Rattus norvegicus
P07335
381
42707
Y100
I
E
D
R
H
G
G
Y
Q
P
S
D
E
H
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508143
326
36755
H90
R
G
F
C
L
P
P
H
C
S
R
G
E
R
R
Chicken
Gallus gallus
P05122
381
42852
Y100
I
E
D
R
H
G
G
Y
K
P
T
D
E
H
K
Frog
Xenopus laevis
NP_001080363
376
42223
Y95
I
E
D
R
H
G
G
Y
K
P
T
D
Q
H
K
Zebra Danio
Brachydanio rerio
NP_775329
381
42865
Y100
I
E
D
R
H
G
G
Y
K
P
T
D
K
H
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P48610
356
39848
K94
E
D
Y
H
G
G
F
K
K
T
D
K
H
P
A
Honey Bee
Apis mellifera
O61367
355
39990
K94
D
Y
H
G
G
F
K
K
T
D
K
H
P
P
K
Nematode Worm
Caenorhab. elegans
Q27535
360
40364
K95
E
E
Y
H
N
G
F
K
A
T
D
T
Q
P
A
Sea Urchin
Strong. purpuratus
P18294
1174
130851
Y514
I
D
A
R
H
G
G
Y
P
K
D
A
V
H
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001169054
381
42707
Y100
I
E
D
R
H
G
G
Y
Q
P
S
D
E
H
K
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
81.9
99.2
94.4
N.A.
96.5
96.5
N.A.
77.9
90.5
83.1
85.8
N.A.
42.7
40.9
37.7
22.4
Protein Similarity:
100
82.1
100
95.9
N.A.
98.6
98.4
N.A.
83.7
96.3
92.3
93.1
N.A.
59
58.7
55.9
28.1
P-Site Identity:
100
100
100
100
N.A.
86.6
93.3
N.A.
6.6
93.3
86.6
86.6
N.A.
13.3
6.6
13.3
46.6
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
20
100
100
100
N.A.
20
6.6
26.6
53.3
Percent
Protein Identity:
N.A.
96.5
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
98.4
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
93.3
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
100
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
7
0
0
0
0
0
7
0
0
7
0
0
14
% A
% Cys:
0
0
0
7
0
0
0
0
7
0
0
0
0
0
0
% C
% Asp:
7
14
60
0
0
0
0
0
0
7
20
67
0
0
0
% D
% Glu:
14
74
7
0
0
0
0
0
0
0
0
0
60
0
0
% E
% Phe:
0
0
7
0
0
7
14
0
0
0
0
0
0
0
0
% F
% Gly:
0
7
0
7
14
87
74
0
0
0
0
7
0
0
0
% G
% His:
0
0
7
14
74
0
0
7
0
0
0
7
7
74
0
% H
% Ile:
74
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
7
20
54
7
7
7
7
0
74
% K
% Leu:
0
0
0
0
7
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
7
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
7
7
0
7
67
0
0
7
20
0
% P
% Gln:
0
0
0
0
0
0
0
0
20
0
0
0
14
0
0
% Q
% Arg:
7
0
0
74
0
0
0
0
0
0
7
0
0
7
7
% R
% Ser:
0
0
0
0
0
0
0
0
0
7
47
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
7
14
20
7
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
7
0
7
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
7
14
0
0
0
0
74
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _